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Friday, August 13, 2010

[chottala.com] multi-resistant, untreatable NDM-1 gene in Indian Hospitals




India refutes 'superbug' claims
It is feared that the bug could be present but undetected in many communities [Getty]
India has forcefully stated that its hospitals are safe after researchers said that medical tourists to the country had caught a new "superbug".
Some Indian politicians on Thursday said that there is a conspiracy against the country's rising medical tourism industry.
A study in The Lancet, a British medical journal, said that a newfound NDM-1 bacteria, or New Delhi metallo-lactamase-1, is a new type of antibiotic-resistant bug that had been carried from India to the UK.
The journal warned that the bug could spread worldwide.
The Indian health ministry reacted angrily in a statement.
"We strongly refute the naming of the enzyme ... and also refute that hospitals in India are not safe for treatment including medical tourism," it said.
"To link this with the safety of surgery in hospitals in India and citing isolated examples to show that ... India is not a safe place to visit, is wrong."
Scaremongering
"It probably is killing lots of people but it happens in the developing world and there's no way of measuring it."
Peter Collignon, head of the infectious diseases department at Canberra Hospital
The ministry said that the report was scaremongering, but did admit that the bacteria could circulate widely with international travel.
The NDM-1 gene was discovered last year by Timothy Walsh of Cardiff University in two types of bacteria carried by a Swedish patient who had been admitted to a hospital in India.
Concern has been heightened because the germ produces an enzyme that is resistant to very strong, last resort antibiotics.
The researchers said that 37 people had been found to be carrying the bug.
Peter Collignon, the head of the infectious diseases department at Canberra Hospital in Australia's capital, also said that three Australians had brought the bug to the country from India.
He said that the cases, including one person who travelled to India for plastic surgery, were the "tip of the iceberg".
'Untreatable' 
"There may well be more because it's difficult to pick up this particular gene unless you've got sophisticated testing," Collignon said.
"We found this multi-resistant, untreatable bug in their urine, luckily not causing too many problems to that person. But it's a real problem if it spreads to others.
"The germ we had was untreatable - there were no drugs we had that could treat it."
Collignon said while one person had contracted the gene during botched plastic surgery, another had worringly picked up the bug in the general community.
"It probably is killing lots of people but it happens in the developing world and there's no way of measuring it."
Collignon, who sits on the World Health Organisation board on antibiotics, said that "abuse" of antibiotics in medicine and agriculture has led to the superbug.
International crackdown
"When you link it to our antibiotics policy ... say it is dangerous to get operated on in India and that you will get more infections, that is totally irrational."
V M Katoch, director general of the Indian Council of Medical Research
He called for a international crackdown on such widespread use and a hygiene campaign to stop the spread of bacteria.
"All of these systems are interlinked through our food. Wherever we use antibiotics and wherever we over-use them we will get superbugs develop and we will get problems," Collignon said.
Medical tourists are flocking to South Asia, with new hospitals offering a range of services with well-trained staff, at about half of the price of western Europe.
V M Katoch, director general of the Indian Council of Medical Research, said that multiple drug resistance was "always a concern".
"But when you draw conclusions that link it to a specific country, then you are going too far," Katoch said.
"When you link it to our antibiotics policy ... say it is dangerous to get operated on in India and that you will get more infections, that is totally irrational."



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